Retrovirus antigens in brains of mice with scrapie- and murine leukemia virus-induced spongiform encephalopathy.
نویسندگان
چکیده
Wild mouse ecotropic virus-induced spongiform encephalomyelopathy pathologically similar to scrapie was associated with the expression of retrovirus antigens in mouse brains. However, scrapie-infected mice with spongiform encephalopathy showed no increased expression of retrovirus antigens in brain. Thus, the pathogenesis of the scrapie spongiform lesion does not appear to involve activation of endogenous retrovirus.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 38 1 شماره
صفحات -
تاریخ انتشار 1982